No.
10S with a 22x10 on that motor does 6890 RPMs, 101A, and 3630W
12S with a 21x10 will try to do 8430 RPMs, which will take 131A and 5750W, which means it won't and probably fry trying.
On 10S, it will do 7025 RPMs, 91A, and 3315W, which is not bad... 246 Watts per pound at 13.5 pounds.
If it were me, and I was limited to 12S, I'd probably have to try the 19x8 PJN... the motor will try to spin it about 9000 RPMs, but will only draw about 82A and produce about 3580 to 3720 Watts.
That's pretty good pitch speed, and the throttle response should be very good. But all the power will be at the very top end of the throttle curve. If you do more XA than 3D, it may work. If you do more 3D than XA, you may want to consider the 21x10 on 10S, and maybe try the 22x8 on 10S, which will be noticeably slower than the 21x10. But again, not sure the motor can manage the bigger props up around 7000+ RPMs.